NECESSARY Project

NECESSARY: New patient-specific functional assessment of the anomalous aortic origin of coronary arteries: stratifying the risk for myocardial ischemia and sudden death.

Project Title

New patient-specific functional assessment of the anomalous aortic origin of coronary arteries: stratifying the risk for myocardial ischemia and sudden death

Acronym

NECESSARY

Partners

Dr. Mauro Lo Rito (Congenital Cardiac Surgery, Radiology Unit, Clinical and Interventional Cardiology, Policlinico San Donato) [PI], Michele Conti (Department of Civil Engineering and Architecture, Univeristy of Pavia) [Operative unit], Dr. Francesco Secchi (Diagnostic Imaging, Policlinico San Donato) [Operative unit], Dr. Mauro Luca Agnifili (Congenital Cardiac Surgery, Radiology Unit, Clinical and Interventional Cardiology, Policlinico San Donato) [Operative unit]

UniPV Funding

€ 160.000,00

Overall Funding

€ 850.300,00

Funding Agency

Italian Ministry Of Health

Call

Ricerca Finalizzata 2019 (GR-2019-12369116)

Duration

2020 – 2023 (3 years)

Short Description

Anomalous Aortic Origin of the Coronary Arteries (AAOCA) is a rare congenital disease that may cause sudden death in young subjects. Currently the decision to undergo corrective surgery is based on the morphologic characteristics without the support of a functional evaluation. The aim is to assess the mechanical compression of the anomalous coronary and the consequent impact in coronary fluid dynamics by means of patient-specific computational simulations of the aortic root and coronary tree. The expectation is that a personalized risk assessment will allow better ischemic risk stratification thus improving indication for surgery.