Research Topics DORIAN

  • Bioprinting and In Vitro Tissue Modeling. Development of three-dimensional human tissue models using advanced bioprinting techniques. The activity focuses on the model-driven formulation and optimization of green bioinks based on natural, biodegradable materials derived from renewable sources, including collagen-based biomaterials.
  • In Vitro Platforms for Environmental Exposure Assessment. Design and validation of bioprinted in vitro platforms to investigate the effects of environmental pollutants, such as microplastics, heavy metals, and airborne particulate matter, on human tissues, enabling controlled, reproducible and human-relevant exposure studies.
  • Computational Modeling. Development of computational models to support the rational design of bioprinted tissue constructs, including the simulation of the diffusion and transport of environmental pollutants within the tissue microenvironment.
  • Mechanical characterization. Multiscale assessment of the impact of pollutants and environmental conditions on the mechanical response of biological tissues, 3D bioprinted models, and biomaterial inks, as well as advanced techniques like nanoindentation.